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In The Church of Jesus Christ of Latter Day Saints' Doctrine and Covenants Section 89 states that tobacco can be used as a herb for sick livestock but is not meant for human use by practitioners of the faith as part of "The Word of Wisdom"

The complexity of feedback mechanisms, whereby gonadal steroids modulate pituitary hormone secretion, along with the concurrent elevation of LH and gonadal androgens in users, makes it difficult to attribute increased testosterone specifically to LH modulation 38